Antibacterial effect of Chromolaena odorata (Awolowo Leaf) aqueous leaf extract on Pseudomonas aeruginosa induced gastrointestinal tract infection in adult Wistar rat

The effect of Chromolaena odorata aqueous leaf extract on Pseudomonas aeruginosa induced gastrointestinal tract infection in adult rats was studied using thirty six (36) wistar rats, whose weights range from 72-100g. were allowed to acclimatize for two weeks and checked fitness through weight check urinalysis. Twelve used toxicological study (LD50) while 24 determine the antibacterial effects extract. 12 LD50 divided into three groups four each other each. significantly high group Q after treatment (4.5±2.12 Cfu/ml) when compared with mean value before (20.0±4.24 Cfu/ml). antibiotic ciprofloxacin higher R (0.00±0.00 (24.0±1.41 But S, count (26.5±13.44 (14.5±4.95 this is because not treated either leave or antibiotics. Conclusively, could be adopted as an alternative against infections especially those due aeruginosa.